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  • HOME
  • DOG BREEDS

    🐕 A - F

    • Australian Shepherd
    • Beagle
    • Boxer
    • Border Collie
    • Cocker Spaniel
    • Corgi
    • Dachshund
    • French Bulldog

    🐩 G - M

    • German Shepherd
    • German Shepherd Wolf
    • Goldendoodle
    • Greyhound
    • Havanese
    • Husky
    • Labradoodle
    • Maltese
    • Mastiff
    • Miniature Husky
    • Miniature Schnauzer
    • Morkie

    🐶 N - Z

    • Pitbull
    • Pomchi
    • Pomeranian
    • Pomsky
    • Poodle
    • Shih Tzu
    • Shorkie
    • Yorkie

    More Articles on Breeds

    Best Dog Food for Rhodesian Ridgebacks DogStruggles

    10 Best Dog Foods for Rhodesian Ridgebacks

    10 January 2022
    11 Smartest Small Dog Breeds Featured Image

    11 Smartest Small Dog Breeds

    10 January 2022

    Stages of Husky Puppy Development

    10 January 2022
    german shepherd belgian malinois featured on dogstruggles

    German Shepherd vs Belgian Malinois – Traits & Comparisons

    10 January 2022
    boxer beagle

    Beagle Boxer Mix – The Complete Boggle Dog Guide!

    10 January 2022
  • DOG FOOD
    • BY BREED
      • For American Bulldogs
      • For Australian Shepherds
      • For Basenjis
      • For Beagles
      • For Blue Heelers
      • For Border Collies
      • For Boxer Puppies
      • For Bull terriers
      • For Cavalier King Charles
      • For Chihuahua Puppies
      • For Cocker Spaniels
      • For Corgi Puppies
      • For Dachshunds
      • For Dalmations
      • For Dobermans
      • For French Bulldog Puppies
      • For German Shepherd Puppies
      • For German Shorthaired Pointers
      • For Golden Retrievers
      • For Great Danes
      • For Greyhounds
      • For Havanese
      • For Hunting Dogs
      • For Jack Russells
      • For Maltipoo
      • For Maltese Puppies
      • For Mastiffs
      • For Miniature Schnauzers
      • For Morkies
      • For Pomeranians  
      • For Poodles
      • For Husky Puppies
      • For Pitbulls
      • For Pugs
      • For Rhodesian Ridgebacks
      • For Rottweilers
      • For Shichons
      • For Saint Bernards
      • For Weimaraners
      • For Yorkies
    • COMPARISON
      • Annamaet
      • Bil-Jac
      • Canine Caviar
      • Evolve
      • Instinct
      • Brands on a Budget
      • Organic Brands
      • Nature’s Logic
      • Nulo
      • Orijen
      • Performatrin Ultra
      • Pro Pac
      • Royal Canin vs Blue Buffalo
      • Sojos
      • Taste of the Wild vs Blue Wilderness
      • Victor
      • Victor Dog Food vs Diamond Naturals
      • Weruva
      • Whole Earth Farm
    • FOR A PURPOSE
      • For Arthritis
      • For Bad Teeth
      • Dehydrated Dog Food
      • High-Calorie
      • High Fiber for Anal Gland Problems
      • Hypoallergenic Foods
      • For IBD 
      • Legume Free
      • Limited Ingredient Foods
      • Low Protein
      • Low Sodium
      • Ollie Dog Food Reviews
      • To Prevent Gas
      • Puppy Milk Replacer
      • For Picky Dogs
      • For Seizures
      • For Sensitive Stomachs
      • For Skin Allergies
      • For Yeast Infections
    • TREATS
      • Dentastix vs Greenies: Which is Better?
      • For Pomeranians
      • For Puppy Training
      • For Yorkies
  • DOG MEDICINE
    • Antihistamines for Allergies
    • Aspirin
    • Benadryl
    • Dewormers
    • DNA Tests
    • Dramamine
    • Ear Cleaners
    • Gabapentin
    • Glucosamine
    • Heartgard
    • Melatonin
    • Nexgard vs Frontline
    • Prednisone
    • Toothpastes
    • Tramadol
    • Trifexis vs Comfortis
    • Xanax
    • Zyrtec
  • DOG SUPPLIES
    • BEDS
      • Bedding for Kennels
      • Bedding for Puppies
      • Chew Proof beds
      • Elevated beds
      • For Australian Shepherds
      • For Beagles
      • For Bernese Mountain Dogs
      • For Border Collies
      • For Boston Terriers
      • For Boxers
      • For Bulldogs
      • For Chihuahuas
      • For Cockapoos
      • For Cocker Spaniels
      • For Corgis
      • For Coton De Tulears
      • For Dachshunds
      • For Dobermans
      • For English Mastiffs
      • For French Bulldogs
      • For German Shepherds
      • For Goldendoodles
      • For Great Danes
      • For Greyhounds
      • For Labradoodles
      • For Mastiffs
      • For Miniature Schnauzers
      • For Pitbulls
      • For Pomeranians
      • For Rhodesian Ridgebacks
      • For Rottweilers
      • For Shih Tzus
      • For Siberian Huskies
      • For Weimaraners
      • For Whippets
      • For Vizslas
      • For Yorkies
      • Heated Beds
      • Luxury Beds
      • Orthopedic Beds
      • Waterproof Beds
    • BRUSHES
      • For Australian Shepherds
      • For Boxer Dogs
      • For Corgis
      • For German Shepherds
      • For Goldendoodles
      • For Golden Retrievers
      • For Havanese
      • For Labradoodles
      • For Maltese
      • For Maltipoos
      • For Poodles
      • For Pitbulls
      • For Pomeranians
      • For Saint Bernards
      • For Shih Tzus
      • For Yorkies
    • COLLARS
      • Bark Collars
      • For Chihuahuas
      • Citronella Bark Collars
      • For Dobermans
      • For German Shepherds
      • Leather Collars
      • Reflective Collars
    • CLIPPERS
      • For Airedale Terriers
      • For Australian Shepherds
      • For Bichon Frise
      • For Border Collies
      • For Coton De Tulears
      • For German Shepherds
      • For Goldendoodles
      • For Havanese
      • For Labradoodles
      • For Lhasa Apso
      • For Maltese
      • For Matted Hair
      • For Miniature Schnauzers
      • For Old English Sheepdogs
      • For Pomeranians
      • For Poodles
      • For Portuguese Water Dogs
      • For Shih Tzus
    • CRATES
      • Crate Covers
      • For Beagles
      • For Border Collies
      • For Boston Terriers
      • For Boxers
      • For Cavalier King Charles Spaniels
      • For Chihuahuas
      • For Dachshunds
      • For Dobermans
      • For English Bulldogs
      • For Goldendoodles
      • For Golden Retrievers
      • For Great Danes
      • For Greyhounds
      • For Huskies
      • For Labradoodles
      • For Mastiffs
      • For Miniature Schnauzers
      • For Pitbulls
      • For Pomeranians
      • Revol Crate
      • For Rottweilers
      • For Separation Anxiety
      • For Shih Tzus
      • For Weimaraners
      • Crate Water Bottle
      • Wooden Dog Crates
      • For Yorkies
    • HARNESSES
      • For American Bulldogs
      • For Beagles
      • For Boxers
      • For Bulldogs
      • For Chihuahuas
      • For Dachshunds
      • For French Bulldogs
      • Freedom No Pull
      • For German Shepherds
      • For Golden Retrievers
      • K9 Harness
      • For Pugs
      • For Rottweilers
      • For Shih Tzu
      • For Siberian Husky
      • For Yorkies
    • LEASHES
      • For Pitbulls
      • For Running
      • Retractable
    • MUZZLES
      • Basket Muzzles
      • For Chihuahuas
      • For Pitbulls
    • NAIL CLIPPERS
      • For Cockapoos
      • For Golden Retrievers
    • TOYS
      • Balls
      • Chew Toys for Pit Bulls
      • For Border Collies
      • For Corgis
      • For Dalmations
      • Frisbees
      • Interactive Toys
      • Playpens
      • For Pomeranians
      • Pools
      • Puppy Chew Toys
      • For Shih Tzus
      • Squeaky Toys
      • Tug Toys
    • SHAMPOO
      • For Bulldogs
      • Flea Shampoos
      • For French Bulldogs
      • For Goldendoodles
      • For Golden Retrievers
      • For Huskies
      • Hypoallergenic Shampoos
      • For Maltese
      • Natural Shampoos for Sensitive Skin
      • Oatmeal Shampoos
      • For Pitbulls
      • For Pomeranians
      • For Poodles
      • For Puppies
      • For Shih Tzu
      • For Yorkies
    • Boston Terrier Sweater
    • Dog Camping Tents
    • Hunting Vests
    • Flea Carpet Powder
    • Strollers
    • Training Books
    • Pet Hair Vacuums
  • BLOG
    • Can My Dog Eat That?
      • Biscuits
      • Cheerios
      • Chia Seeds
      • Cinnamon
      • Crackers
      • Dairy
        • Cheese
        • Vanilla Ice Cream
      • Eggs
      • Falafel
      • Fruit
        • Apples
        • Avocado
        • Bananas
        • Blackberries
        • Coconut
        • Mangoes
        • Strawberries
        • Tomatoes
        • Zucchini
      • Honey
      • Hot Sauce
      • Instant Noodles
      • Meat
        • Chicken Bones
        • Chicken Skin
        • Ham Bones
        • Salami
        • Sausage
        • Steak
        • Trout
        • Tuna
        • Turkey
      • Oatmeal
      • Peanut Butter
      • Pink Salt
      • Pita Bread
      • Pizza Crust
      • Popcorn
      • Potato
      • Sunflower Seeds
      • Vegetables
        • Beans
        • Brussel Sprouts
        • Carrots
        • Green Peppers
        • Lettuce
        • Onions
        • Truffles
        • Yellow Squash
    • Cats vs. Dogs
    • Exotic Dog Breeds
      • African
      • Chinese
      • Cleanest
      • Curly Haired
      • English
      • Fastest
      • Long-Legged
      • Small White
      • Smartest Small Breeds
    • Guides
      • Benefits and Risks of a Raw Diet
      • Can I Give My Dog Aspirin?
      • Does CBD Work for Dogs? 
      • Dogs Insurance Will Not Cover
      • Fixing Your Dogs Fear of Bathing
      • Guide to Crate Training a Puppy
      • Guide To Dog Digestion
      • How Long Does It Take To Groom a Dog?
      • How Often Can I Bathe My Dog With Flea Shampoo
      • How Often Should You Wash Your Dog?
      • Why Do Dogs Eat Cat Poop?
      • Why Does My Dog Pee On My Bed?
    • GPS Chips
    • How To Guides
      • Keep Dog Off Bed
      • Leash Train a Dog That Won’t Walk
      • Make a Leash Out of Paracord
      • Make a Leather Collar
      • Measure a Dog For a Muzzle
      • Put a Dog Tag on a Collar
      • Sedate a Dog for Grooming
      • Sharpen Nail Clippers
      • Stop Dog from Digging
      • Store Dry Dog Food Long Term
      • Train Dog for Protection
      • Train Dog to Sit Down
      • Wash a Dog Bed With Stuffing
    • Superpowers Dogs Have
    • Why Do Dogs
      • Cough
      • Eat Grass
      • Eat Socks
      • Hump The Air
      • Keep Licking Their Paws
      • Look Sad
      • Penises Stay Out
      • Put Their Ears Back
      • Sleep So Much
      • Wag their Tail
      • Watch TV
    • Why Walking Your Dog is Good for You
  • ABOUT US
  • HOME
  • DOG BREEDS

    🐕 A - F

    • Australian Shepherd
    • Beagle
    • Boxer
    • Border Collie
    • Cocker Spaniel
    • Corgi
    • Dachshund
    • French Bulldog

    🐩 G - M

    • German Shepherd
    • German Shepherd Wolf
    • Goldendoodle
    • Greyhound
    • Havanese
    • Husky
    • Labradoodle
    • Maltese
    • Mastiff
    • Miniature Husky
    • Miniature Schnauzer
    • Morkie

    🐶 N - Z

    • Pitbull
    • Pomchi
    • Pomeranian
    • Pomsky
    • Poodle
    • Shih Tzu
    • Shorkie
    • Yorkie

    More Articles on Breeds

    Best Dog Food for Rhodesian Ridgebacks DogStruggles

    10 Best Dog Foods for Rhodesian Ridgebacks

    10 January 2022
    11 Smartest Small Dog Breeds Featured Image

    11 Smartest Small Dog Breeds

    10 January 2022

    Stages of Husky Puppy Development

    10 January 2022
    german shepherd belgian malinois featured on dogstruggles

    German Shepherd vs Belgian Malinois – Traits & Comparisons

    10 January 2022
    boxer beagle

    Beagle Boxer Mix – The Complete Boggle Dog Guide!

    10 January 2022
  • DOG FOOD
    • BY BREED
      • For American Bulldogs
      • For Australian Shepherds
      • For Basenjis
      • For Beagles
      • For Blue Heelers
      • For Border Collies
      • For Boxer Puppies
      • For Bull terriers
      • For Cavalier King Charles
      • For Chihuahua Puppies
      • For Cocker Spaniels
      • For Corgi Puppies
      • For Dachshunds
      • For Dalmations
      • For Dobermans
      • For French Bulldog Puppies
      • For German Shepherd Puppies
      • For German Shorthaired Pointers
      • For Golden Retrievers
      • For Great Danes
      • For Greyhounds
      • For Havanese
      • For Hunting Dogs
      • For Jack Russells
      • For Maltipoo
      • For Maltese Puppies
      • For Mastiffs
      • For Miniature Schnauzers
      • For Morkies
      • For Pomeranians  
      • For Poodles
      • For Husky Puppies
      • For Pitbulls
      • For Pugs
      • For Rhodesian Ridgebacks
      • For Rottweilers
      • For Shichons
      • For Saint Bernards
      • For Weimaraners
      • For Yorkies
    • COMPARISON
      • Annamaet
      • Bil-Jac
      • Canine Caviar
      • Evolve
      • Instinct
      • Brands on a Budget
      • Organic Brands
      • Nature’s Logic
      • Nulo
      • Orijen
      • Performatrin Ultra
      • Pro Pac
      • Royal Canin vs Blue Buffalo
      • Sojos
      • Taste of the Wild vs Blue Wilderness
      • Victor
      • Victor Dog Food vs Diamond Naturals
      • Weruva
      • Whole Earth Farm
    • FOR A PURPOSE
      • For Arthritis
      • For Bad Teeth
      • Dehydrated Dog Food
      • High-Calorie
      • High Fiber for Anal Gland Problems
      • Hypoallergenic Foods
      • For IBD 
      • Legume Free
      • Limited Ingredient Foods
      • Low Protein
      • Low Sodium
      • Ollie Dog Food Reviews
      • To Prevent Gas
      • Puppy Milk Replacer
      • For Picky Dogs
      • For Seizures
      • For Sensitive Stomachs
      • For Skin Allergies
      • For Yeast Infections
    • TREATS
      • Dentastix vs Greenies: Which is Better?
      • For Pomeranians
      • For Puppy Training
      • For Yorkies
  • DOG MEDICINE
    • Antihistamines for Allergies
    • Aspirin
    • Benadryl
    • Dewormers
    • DNA Tests
    • Dramamine
    • Ear Cleaners
    • Gabapentin
    • Glucosamine
    • Heartgard
    • Melatonin
    • Nexgard vs Frontline
    • Prednisone
    • Toothpastes
    • Tramadol
    • Trifexis vs Comfortis
    • Xanax
    • Zyrtec
  • DOG SUPPLIES
    • BEDS
      • Bedding for Kennels
      • Bedding for Puppies
      • Chew Proof beds
      • Elevated beds
      • For Australian Shepherds
      • For Beagles
      • For Bernese Mountain Dogs
      • For Border Collies
      • For Boston Terriers
      • For Boxers
      • For Bulldogs
      • For Chihuahuas
      • For Cockapoos
      • For Cocker Spaniels
      • For Corgis
      • For Coton De Tulears
      • For Dachshunds
      • For Dobermans
      • For English Mastiffs
      • For French Bulldogs
      • For German Shepherds
      • For Goldendoodles
      • For Great Danes
      • For Greyhounds
      • For Labradoodles
      • For Mastiffs
      • For Miniature Schnauzers
      • For Pitbulls
      • For Pomeranians
      • For Rhodesian Ridgebacks
      • For Rottweilers
      • For Shih Tzus
      • For Siberian Huskies
      • For Weimaraners
      • For Whippets
      • For Vizslas
      • For Yorkies
      • Heated Beds
      • Luxury Beds
      • Orthopedic Beds
      • Waterproof Beds
    • BRUSHES
      • For Australian Shepherds
      • For Boxer Dogs
      • For Corgis
      • For German Shepherds
      • For Goldendoodles
      • For Golden Retrievers
      • For Havanese
      • For Labradoodles
      • For Maltese
      • For Maltipoos
      • For Poodles
      • For Pitbulls
      • For Pomeranians
      • For Saint Bernards
      • For Shih Tzus
      • For Yorkies
    • COLLARS
      • Bark Collars
      • For Chihuahuas
      • Citronella Bark Collars
      • For Dobermans
      • For German Shepherds
      • Leather Collars
      • Reflective Collars
    • CLIPPERS
      • For Airedale Terriers
      • For Australian Shepherds
      • For Bichon Frise
      • For Border Collies
      • For Coton De Tulears
      • For German Shepherds
      • For Goldendoodles
      • For Havanese
      • For Labradoodles
      • For Lhasa Apso
      • For Maltese
      • For Matted Hair
      • For Miniature Schnauzers
      • For Old English Sheepdogs
      • For Pomeranians
      • For Poodles
      • For Portuguese Water Dogs
      • For Shih Tzus
    • CRATES
      • Crate Covers
      • For Beagles
      • For Border Collies
      • For Boston Terriers
      • For Boxers
      • For Cavalier King Charles Spaniels
      • For Chihuahuas
      • For Dachshunds
      • For Dobermans
      • For English Bulldogs
      • For Goldendoodles
      • For Golden Retrievers
      • For Great Danes
      • For Greyhounds
      • For Huskies
      • For Labradoodles
      • For Mastiffs
      • For Miniature Schnauzers
      • For Pitbulls
      • For Pomeranians
      • Revol Crate
      • For Rottweilers
      • For Separation Anxiety
      • For Shih Tzus
      • For Weimaraners
      • Crate Water Bottle
      • Wooden Dog Crates
      • For Yorkies
    • HARNESSES
      • For American Bulldogs
      • For Beagles
      • For Boxers
      • For Bulldogs
      • For Chihuahuas
      • For Dachshunds
      • For French Bulldogs
      • Freedom No Pull
      • For German Shepherds
      • For Golden Retrievers
      • K9 Harness
      • For Pugs
      • For Rottweilers
      • For Shih Tzu
      • For Siberian Husky
      • For Yorkies
    • LEASHES
      • For Pitbulls
      • For Running
      • Retractable
    • MUZZLES
      • Basket Muzzles
      • For Chihuahuas
      • For Pitbulls
    • NAIL CLIPPERS
      • For Cockapoos
      • For Golden Retrievers
    • TOYS
      • Balls
      • Chew Toys for Pit Bulls
      • For Border Collies
      • For Corgis
      • For Dalmations
      • Frisbees
      • Interactive Toys
      • Playpens
      • For Pomeranians
      • Pools
      • Puppy Chew Toys
      • For Shih Tzus
      • Squeaky Toys
      • Tug Toys
    • SHAMPOO
      • For Bulldogs
      • Flea Shampoos
      • For French Bulldogs
      • For Goldendoodles
      • For Golden Retrievers
      • For Huskies
      • Hypoallergenic Shampoos
      • For Maltese
      • Natural Shampoos for Sensitive Skin
      • Oatmeal Shampoos
      • For Pitbulls
      • For Pomeranians
      • For Poodles
      • For Puppies
      • For Shih Tzu
      • For Yorkies
    • Boston Terrier Sweater
    • Dog Camping Tents
    • Hunting Vests
    • Flea Carpet Powder
    • Strollers
    • Training Books
    • Pet Hair Vacuums
  • BLOG
    • Can My Dog Eat That?
      • Biscuits
      • Cheerios
      • Chia Seeds
      • Cinnamon
      • Crackers
      • Dairy
        • Cheese
        • Vanilla Ice Cream
      • Eggs
      • Falafel
      • Fruit
        • Apples
        • Avocado
        • Bananas
        • Blackberries
        • Coconut
        • Mangoes
        • Strawberries
        • Tomatoes
        • Zucchini
      • Honey
      • Hot Sauce
      • Instant Noodles
      • Meat
        • Chicken Bones
        • Chicken Skin
        • Ham Bones
        • Salami
        • Sausage
        • Steak
        • Trout
        • Tuna
        • Turkey
      • Oatmeal
      • Peanut Butter
      • Pink Salt
      • Pita Bread
      • Pizza Crust
      • Popcorn
      • Potato
      • Sunflower Seeds
      • Vegetables
        • Beans
        • Brussel Sprouts
        • Carrots
        • Green Peppers
        • Lettuce
        • Onions
        • Truffles
        • Yellow Squash
    • Cats vs. Dogs
    • Exotic Dog Breeds
      • African
      • Chinese
      • Cleanest
      • Curly Haired
      • English
      • Fastest
      • Long-Legged
      • Small White
      • Smartest Small Breeds
    • Guides
      • Benefits and Risks of a Raw Diet
      • Can I Give My Dog Aspirin?
      • Does CBD Work for Dogs? 
      • Dogs Insurance Will Not Cover
      • Fixing Your Dogs Fear of Bathing
      • Guide to Crate Training a Puppy
      • Guide To Dog Digestion
      • How Long Does It Take To Groom a Dog?
      • How Often Can I Bathe My Dog With Flea Shampoo
      • How Often Should You Wash Your Dog?
      • Why Do Dogs Eat Cat Poop?
      • Why Does My Dog Pee On My Bed?
    • GPS Chips
    • How To Guides
      • Keep Dog Off Bed
      • Leash Train a Dog That Won’t Walk
      • Make a Leash Out of Paracord
      • Make a Leather Collar
      • Measure a Dog For a Muzzle
      • Put a Dog Tag on a Collar
      • Sedate a Dog for Grooming
      • Sharpen Nail Clippers
      • Stop Dog from Digging
      • Store Dry Dog Food Long Term
      • Train Dog for Protection
      • Train Dog to Sit Down
      • Wash a Dog Bed With Stuffing
    • Superpowers Dogs Have
    • Why Do Dogs
      • Cough
      • Eat Grass
      • Eat Socks
      • Hump The Air
      • Keep Licking Their Paws
      • Look Sad
      • Penises Stay Out
      • Put Their Ears Back
      • Sleep So Much
      • Wag their Tail
      • Watch TV
    • Why Walking Your Dog is Good for You
  • ABOUT US
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View All Result
Dog struggles
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Home Dog medicine

Nexgard vs Frontline

Sarah Robinson by Sarah Robinson
8 January 2022
in Dog medicine
labrador biting/itchy itself
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This post contains affiliate links, and we will be compensated if you make a purchase after clicking on our links. Learn more.

To weigh up NexGard and Frontline, let’s indulge in a spot of time travel.

Go back a couple of decades and your choices for getting rid of fleas and ticks were extremely limited.

The dogs your parents owned were most likely sprayed with organo-phosphate chemicals from an aerosol can.

This had so many downsides, such as the spray only lasted a week then reapplication was necessary, and the dog increasingly hated the sound of the aerosol so application became more and more difficult.

In addition, organo-phosphates are toxic to dogs as well as fleas – it’s just a matter of dose, so you stood a chance of killing not just the parasites.

All of this means that dogs and dog owners alike breathed a huge sigh of relief when Merial developed Frontline, and it first came on the market.

Originally Frontline was available as a pump spray but, thank goodness, it only needed application every couple of months. Then later on, better still.

Merial brought out a spot-on version that had everything: ease of application, safety, and effectiveness.

However, times change and science moves on.

In the ever-present battle against fleas and ticks, the latest raft of products are applied to the dog at all, but swallowed…as a palatable tablet.

Enter the next generation and… NexGard.

Weighing up NexGard for dogs vs Frontline, has the latter had its day, or is there still a place for this once revolutionary product?

Let’s compare the two products and find out. (And for those who can’t stand the suspense, yes, Frontline does still have a place.)

Frontline-Small

Frontline 5-22 Lb's (Small)
CLICK FOR BEST PRICE
Chewy.com
Frontline-Medium
Frontline 23-44 Lb's (Medium)
CLICK FOR BEST PRICE
Chewy.com

Frontline-Large

Frontline 45-88 Lb's (Large)
CLICK FOR BEST PRICE
Chewy.com

Frontline-Extra-Large

Frontline 89-132 Lb's (Extra Large)
CLICK FOR BEST PRICE
Chewy.com

1. Why Frontline still Counts

When comparing Frontline vs NexGard is tempting to compare Frontline to a push-bike and NexGard a motorbike.

This is because they both do similar jobs but NexGard is more sophisticated and has different pros and cons.

Whether a push-bike or motorbike is best suited to you best depends on your needs.

For example, let’s say your dog has fleas and you need the problem sorted fast.

You can’t get to the vets (to get a prescription for NexGard) and you’re scratching around for an effective solution.

Well, Frontline could be the answer.

As well as efficiently killing fleas and ticks, Frontline is non-prescription.

This means you can buy it through certain pharmacies and pet superstores without needing a script from your vet.

These outlets have staff that has been on a special course which enables them to sell the product.

Sure, the vendor will quiz you to ensure it’s the right (and safe) product for you, but then that’s it.

Hand over the cash and walk out with the Frontline. [NB. Frontline Plus is a subtly different product which includes a wormer, and this does require a prescription]

Contrast this with NexGard, which is a prescription-only product.

This means a visit to the vet for a checkup prior to prescribing the product.

Actually, this isn’t as expensive as it sounds because most vets offer free checks, prior to supplying the product.

And if you don’t want to pay clinic prices, then the vet will charge you to write a script for it.

Another great thing that means Frontline is still relevant is its spectrum of activity.

Comparing Frontline vs NexGard, the former kill a wider range of external parasites including:

  • Fleas
  • Lice: Felicola and Trichodectes species
  • Ticks: Ixodes and Rhipicephalus species
  • Cheyletiella (the walking dandruff mite.)

NexGard kills fleas and ticks BUT (and this is where it starts to get even more confusing) it is effective against different tick species to Frontline.

This matters because NexGard (but not Frontline) is effective against Dermacentor (the American dog tick) which carries Rocky Mountain spotted fever.

Thus there is a clear winner between NexGard or Frontline if the pet parent concerned about Rocky Mountain spotted fever prevention, means NexGard is the better option.

Some of the other advantages of Frontline are that it comes in both a spray (so you can have one product and use it for several dogs of different sizes) or a spot on (super easy to use.)
Indeed, the spray is also useful because once treated, the dog is protected against fleas for three months – instead of the 30 days offered by NexGard.

More subtle still is that Frontline stays on the outside of the dog.

The active ingredient, Fipronil, sits in the hair follicles and is released slowly over time.

This contrasts with Nexgard which is a systemic product, meaning that it enters the bloodstream.

In turn, this produces the arguable advantage that whereas a flea and tick needs to bite to take in NexGard’s active ingredient, this is not the case with Frontline.

A flea or tick merely has to come in contact with the coat in order to die.

This last point is important if you have a pet that suffers the itchy scabs and discomfort of flea allergic dermatitis.

The allergic reaction is caused by the flea injecting their saliva into the dog’s skin.

Thus, in an ideal world, the flea doesn’t need to bite in order to die (as for NexGard).

And last but certainly not least, Frontline is slightly faster at killing parasites.

Why does this matter?

Let’s look at this in more detail in the next section.

2. Concerns about Tick Control

Ticks have a small fan club.

Hardly anyone likes ticks.

They are creepy-looking, feed on blood, and transmit disease.

Indeed, they carry some pretty horrible diseases such as Rocky Mountain spotted fever, Lyme’s disease, Ehlirichia, and Babesiosis to name but a few.

To pass on disease an infected tick must bite the host and feed.

The tick’s infected saliva is passed into the dog’s bloodstream and infection established.

However, there is a chink of light in this gloom because a tick needs to be attached for 24 hours before it transmits the disease.

The implication of this is that the faster the tick dies the better.

On the plus side, NexGard kills the Deer ticks linked to serious illness BUT the bad news is that it takes 48 hours to do it.

Talk about locking the stable door after the horse has bolted! In contrast, Frontline takes 24 – 48 hours to kill ticks, so these unpleasant parasites do die faster.

Actually, the take-home message with regards to killing ticks is not necessarily that one product is superior to the other, but more it’s important to realize you should not rely 100% on anti-tick products.

The concerned pet parent should use both a tick-killing product AND perform daily tick checks on their pet.

Since neither products repel ticks (discourages them from jumping on board), they rely on killing the tick once it is attached, meaning they have a chance to transfer disease.

If tick death takes too long to prevent disease transmission, then you need to remove the tick yourself to fully protect the pet.

The good news is that when you use either NexGard or Frontline, the tick’s grip is much weaker as he starts to feel unwell, sickens, and eventually dies.

Thus it’s a whole lot easier to get the tick off cleanly with NexGard or Frontline, than with neither.

In short, check your dog over daily for ticks and equip yourself with a tick hook to flick off those pesky critters before they cause a problem.

3. Why NexGard is Promising

Given what we’ve just said about tick death, you could be forgiven for wondering why NexGard has generated such a buzz.

On the surface, it’s pretty similar to Frontline, except it’s a tablet.

Actually, as it turns out, doing what it does, and being in a tablet form is a big deal.

There are lots of reasons why a pet parent might prefer to use the simplicity of a treat-like tablet that their dog gobbles down, over applying a spot-on product.

For a start, not all dogs are fans of spot-on products.

Some plain don’t like having something sticky put on the back of their neck, whilst for others, a thick coat makes it difficult to get the liquid in contact with the skin.

Then there’s the issue of having wet fur that needs to be allowed to dry.

This means using a spot on (or spray for that matter) on a much-loved dog when kids are around can be tricky.

You have to pick your moment so that the Frontline can dry in before the kids hug the dog.

The great advantage with a tablet such as NexGard is that it’s a tasty treat.

The dog wolfs it down – end of the problem.

The pill is on the inside and no need to worry about wiping or washing the product away.

And in case you’re wondering since NexGard only treats external parasites (as does Frontline) so where does heartworm fit in.

The answer is that NexGard is safe to give alongside most heartworm preventatives, so that’s another aspect you don’t need to worry about.

As for the downsides of NexGard…well, it is a systemic product, meaning it’s absorbed into the bloodstream.

The product is perfectly safe and has been through extensive testing to prove it’s safe, but not everyone likes the idea of putting chemicals into their dog’s body.

What this also means is, as we mentioned earlier, the flea or tick needs to bite and suck blood in order to take in the active ingredient, afoxolaner.

This is such great news if your dog suffers flea allergic dermatitis as the harm (injecting flea saliva) has already been done.

4. Which should you use: NexGard vs Frontline?

Remember the dark, itchy days of organophosphate flea sprays?

We don’t want to go back those times when fleas were rife because controlling them was such hard work (and dangerous for the dog.)

Modern products such as the two discussed here give us great options.

Yes, there are pros and cons, but the overall story is hugely positive.

Which product to use may seem confusing, but know that you won’t go very far wrong whichever you choose.

To decide which is the best option for your dog think about factors such as:

  • Do I need a non-prescription product?
  • Is my dog likely to get wet soon after the application?
  • Will my kids insist on hugging the dog straight away?
  • How significant is the risk of tick-borne diseases in my region?
  • Is my dog easy to give treats to?
  • How does the dog react to spot-on treatments?
  • Do you have several dogs of different sizes?
  • Is your dog near naked flames?

Let’s look at a couple of scenarios and the options open to you.

If you’re on a limited budget and own several dogs, then Frontline spray is a good option.

This enables you to use the one spray on all the dogs, as long as you follow the recommended dosing advice.

Similarly, if you have a small child who uses your Golden retriever as a walking frame and clambers all over them, you may want to consider NexGard.

The advantage of there being no product to rub off or transfer to human skin makes it an attractive proposition.

On the negative side, a dramatic downside of Frontline is that it’s flammable.

If you were thinking of dosing your dog near a campfire, then drop the idea as its’ not a good one.

Last but certainly not least when thinking about NexGard for dogs vs Frontline, is the cost.

Frontline, specifically Frontline spray, works out considerably cheaper (and don’t forget there is no prescription fee involved from the vet).

The cost of a 3 month supply of NexGard for a 10lb dog, costs around the same as a whooping 500ml Frontline spray bottle.

The latter will last a considerable amount of time and treat several dogs, so cost-wise you know it makes sense to choose the Frontline.

So which will you go for?

The new kid on the block (NexGard tablets) or an established, does what it says on the label product, Frontline.

NexGard or Frontline?

You decide.

Read our comprehensive guide on Dog Medication here. 

The Review

Frontline vs. Nexgard

4.8 Score

Frontline vs Nexgard, Frontline is non-prescription and Nexgard is a prescription-only treatment. Both work just as well!

Review Breakdown

  • Cost
  • Effectiveness

Frontline vs. Nexgard DEALS

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Sarah Robinson

Sarah Robinson

Dr Sarah Robinson attended veterinary school at Oklahoma State University receiving a D.V.M. in 2008. Sarah’s longtime interest is to help people to better communicate with their pet companions, and in doing so, to help them to strengthen their relationships with their dogs and cats. Sarah has published numerous articles on canine feeding in pet related magazines, veterinary journals and leading natural health web sites.

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